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THE NORWEGIAN CENTRe FOR MOVEMENT DISORDERS

Publications

Listed below are publications by NKB for the period: 2010-2023, as well as selected publications from before 2010.

 

  1. Eidem LE , Birkeland E , Austdal M , Bårdsen K , Lange J , Alves G , Berven F, Nilsen MM , Herlofson K , Tysnes OB, Omdal R. Fatigue in Parkinson's Disease: A Proteomic Study of Cerebrospinal Fluid. Mov Disord. 2024 Jan 20. doi: 10.1002/mds.29715. Online ahead of print.

PMID: 38243743

  1. Tufekcioglu Z, Lange J, Pedersen KF, Tysnes OB, Alves G, Emre M. Cognitive Profile in Parkinson's Disease Dementia Patients with Low versus Normal Cerebrospinal Fluid Amyloid Beta. Dement Geriatr Cogn Dis Extra. 2023 Oct 26;13(1):39-47. doi: 10.1159/000534552. eCollection 2023 Jan-Dec.

PMID: 38025590

  1. Erga AH, Hetland J, Braatveit K. Patients with cognitive deficits and substance use disorders, a clinical population in need of focused attention. Front Psychiatry. 2023 Oct 12;14:1281914. doi: 10.3389/fpsyt.2023.1281914. eCollection 2023.

PMID: 37904852

  1. Maple-Grødem J, Ushakova A, Pedersen KF, Tysnes OB, Alves G, Lange J. Identification of diagnostic and prognostic biomarkers of PD using a multiplex proteomics approach. Neurobiol Dis. 2023 Oct 1;186:106281. doi: 10.1016/j.nbd.2023.106281. Epub 2023 Sep 4.

PMID: 37673381

  1. Dietrichs E, Alves G, Benjaminsen E, Johansen KK, Tysnes OB. E. Dietrichs og medarbeidere svarer. Tidsskr Nor Laegeforen. 2023 Sep 4;143(12). doi: 10.4045/tidsskr.23.0533. Print 2023 Sep 5.

PMID: 37668124

  1. Oftedal L, Lange J, Pedersen KF, Erga AH, Dalen I, Tysnes OB, Alves G, Maple-Grødem J. Early GCase activity is a predictor of long-term cognitive decline in Parkinson's disease. Transl Neurodegener. 2023 Aug 28;12(1):41. doi: 10.1186/s40035-023-00373-x.

PMID: 37635244

  1. Oftedal L, Maple-Grødem J, Tysnes OB, Alves G, Lange J. Seed Amplification Assay as a Diagnostic Tool in Newly-Diagnosed Parkinson's Disease. J Parkinsons Dis. 2023;13(5):841-844. doi: 10.3233/JPD-230065.

PMID: 37393438

  1. Maria Camila Gonzalez MD, Diego Alejandro Tovar-Rios MSc, Guido Alves MD, PhD, Ingvild Dalen PhD, Caroline H. Williams-Gray MD, PhD, Marta Camacho MSc, Lars Forsgren , MD, PhD, David Bäckström MD, PhD, Rachael A. Lawson PhD, Angus D. Macleod MD, PhD, Carl E. Counsell MD, Claire Paquet MD, PhD, Carlo DeLena MD, Fabrizia D'Antonio MD, PhD, Andrea Pilotto MD, Alessandro Padovani MD, PhD, Frédéric Blanc MD, PhD, Cristian Falup-Pecurariu MD, Simon J.G. Lewis MD, Konrad Rejdak MD, PhD, Ewa Papuc MD, PhD, Jakub Hort MD, PhD, Zuzana Nedelska MD, John O'Brien MD, Laura Bonanni MD, PhD, Marta Marquié MD, PhD, Mercè Boada MD, PhD, Vanesa Pytel MD, PhD, Carla Abdelnour MD, PhD, Daniel Alcolea MD, PhD, Katrin Beyer PhD, Ole-Bjørn Tysnes MD, PhD, Dag Aarsland MD, PhD, Jodi Maple-Grødem PhD. Cognitive and Motor Decline in Dementia with Lewy Bodies and Parkinson's Disease Dementia. Mov Disord Clin Pract. 2023 May 5;10(6):980-986. doi: 10.1002/mdc3.13752. eCollection 2023 Jun.

PMID: 37332651

  1. Pedersen CC, Ushakova A, Skogseth RE, Alves G, Tysnes OB, Aarsland D, Lange J, Maple-Grødem J. Inflammatory Biomarkers in Newly Diagnosed Patients With Parkinson Disease and Related Neurodegenerative Disorders. Neurol Neuroimmunol Neuroinflamm. 2023 May 31;10(4):e200132. doi: 10.1212/NXI.0000000000200132. Print 2023 Jul.

PMID: 37258413

  1. Dietrichs E, Alves G, Benjaminsen E, Johansen KK, Tysnes OB. Treatment of motor symptoms in Parkinson's disease. Tidsskr Nor Laegeforen. 2023 May 4;143(7). doi: 10.4045/tidsskr.22.0804. Print 2023 May 9.

PMID: 37158528

  1. Hetland J, Hagen E, Lundervold AJ, Erga AH. Performance on Cognitive Screening Tests and Long-Term Substance Use Outcomes in Patients with Polysubstance Use Disorder. Eur Addict Res. 2023;29(2):150-159. doi: 10.1159/000528921. Epub 2023 Apr 20.

PMID: 37080181

  1. Abdelnour C, Gonzalez MC, Gibson LL, Poston KL, Ballard CG, Cummings JL, Aarsland D. Dementia with Lewy Bodies Drug Therapies in Clinical Trials: Systematic Review up to 2022. Neurol Ther. 2023 Jun;12(3):727-749. doi: 10.1007/s40120-023-00467-8. Epub 2023 Apr 5.

PMID: 37017910

  1. Erga AH, Alves G, Leentjens AFG. The ePark study protocol: A decentralized trial of individual video-assisted cognitive behavioural therapy for depressive disorder in Parkinson's disease. Contemp Clin Trials Commun. 2023 Feb 3;32:101080. doi: 10.1016/j.conctc.2023.101080. eCollection 2023 Apr.

PMID: 36817735

  1. Belfrage A, Mjølhus Njå AL, Lunde S, Årstad J, Fodstad EC, Lid TG, Erga AH. Traumatic experiences and PTSD symptoms in substance use disorder: A comparison of recovered versus current users. Nordisk Alkohol Nark. 2023 Feb;40(1):61-75. doi: 10.1177/14550725221122222. Epub 2022 Nov 4.

PMID: 36793481

  1. Dick F, Tysnes OB, Alves GW, Nido GS, Tzoulis C. Altered transcriptome-proteome coupling indicates aberrant proteostasis in Parkinson's disease. iScience. 2023 Jan 4;26(2):105925. doi: 10.1016/j.isci.2023.105925. eCollection 2023 Feb 17.

PMID: 36711240

  1. Fodstad EC, Ushakova A, Pallesen S, Hagen E, Erga AH, Erevik EK. Personality and substance use disorder: Characteristics as measured by NEO-personality inventory-revised. Front Psychol. 2022 Nov 7;13:982763. doi: 10.3389/fpsyg.2022.982763. eCollection 2022.

PMID: 36420387

  1. Liu G, Ni C, Zhan J, Li W, Luo J, Liao Z, Locascio JJ, Xian W, Chen L, Pei Z, Corvol JC, Maple-Grødem J, Campbell MC, Elbaz A, Lesage S, Brice A, Hung AY, Schwarzschild MA, Hayes MT, Wills AM, Ravina B, Shoulson I, Taba P, Kõks S, Beach TG, Cormier-Dequaire F, Alves G, Tysnes OB, Perlmutter JS, Heutink P, van Hilten JJ, Barker RA, Williams-Gray CH, Scherzer CR; International Genetics of Parkinson Disease Progression (IGPP) Consortium. Mitochondrial haplogroups and cognitive progression in Parkinson's disease. Brain. 2022 Nov 8:awac327. doi: 10.1093/brain/awac327. Online ahead of print.

PMID: 36343661

  1. Oftedal L, Maple-Grødem J, Dalen I, Tysnes OB, Pedersen KF, Alves G, Lange J. Association of CSF Glucocerebrosidase Activity With the Risk of Incident Dementia in Patients With Parkinson Disease. Neurology. 2022 Oct 17:10.1212/WNL.0000000000201418. doi: 10.1212/WNL.0000000000201418. Online ahead of print.

PMID: 36253102

  1. Helliesen JS, Kristiansen I, Brekke HK, Støkket RS, Bye A. Nutrition impact symptoms and the risk of malnutrition in people with Parkinson's disease: A cross-sectional study. J Hum Nutr Diet. 2023 Feb;36(1):40-50. doi: 10.1111/jhn.13070. Epub 2022 Aug 26.

PMID: 35897145

  1. Counsell C, Giuntoli C, Khan QI, Maple-Grødem J, Macleod AD. The incidence, baseline predictors, and outcomes of dementia in an incident cohort of Parkinson's disease and controls. J Neurol. 2022 Aug;269(8):4288-4298. doi: 10.1007/s00415-022-11058-2. Epub 2022 Mar 21.

PMID: 35307754

  1. Flønes IH, Nyland H, Sandnes DA, Alves GW, Tysnes OB, Tzoulis C. Early Forms of α-Synuclein Pathology Are Associated with Neuronal Complex I Deficiency in the Substantia Nigra of Individuals with Parkinson's Disease.

Biomolecules. 2022 May 25;12(6):747. doi: 10.3390/biom12060747.

PMID: 35740871

  1. Borda MG, Pérez-Zepeda MU, Jaramillo-Jimenez A, Chaudhuri KR, Tovar-Rios DA, Wallace L, Batzu L, Rockwood K, Tysnes OB, Aarsland D, Alves G. Frailty in Parkinson's disease and its association with early dementia: A longitudinal study. Parkinsonism Relat Disord. 2022 May 13;99:51-57. doi: 10.1016/j.parkreldis.2022.05.004. Online ahead of print.

PMID: 35598420

  1. Gonzalez MC, Dalen I, Maple-Grødem J, Tysnes OB, Alves G. Parkinson's disease clinical milestones and mortality. NPJ Parkinsons Dis. 2022 May 12;8(1):58. doi: 10.1038/s41531-022-00320-z.

PMID: 35550520

  1. Guitton R, Dölle C, Alves G, Ole-Bjørn T, Nido GS, Tzoulis C. Ultra-deep whole genome bisulfite sequencing reveals a single methylation hotspot in human brain mitochondrial DNA. Epigenetics. 2022 Mar 7:1-16. doi: 10.1080/15592294.2022.2045754. Online ahead of print.

PMID: 35253628

  1. Erga AH, Maple-Grødem J, Alves G. Cannabis use in Parkinson's disease-A nationwide online survey study. Acta Neurol Scand. 2022 Jun;145(6):692-697. doi: 10.1111/ane.13602. Epub 2022 Feb 17.

PMID: 35178701

  1. Szwedo AA, Dalen I, Pedersen KF, Camacho M, Bäckström D, Forsgren L, Tzoulis C, Winder-Rhodes S, Hudson G, Liu G, Scherzer CR, Lawson RA, Yarnall AJ, Williams-Gray CH, Macleod AD, Counsell CE, Tysnes OB, Alves G, Maple-Grødem J; Parkinson's Incidence Cohorts Collaboration. GBA and APOE Impact Cognitive Decline in Parkinson's Disease: A 10-Year Population-Based Study. Mov Disord. 2022 May;37(5):1016-1027. doi: 10.1002/mds.28932. Epub 2022 Feb 2.

PMID: 35106798

  1. Bhan A, Jacobsen C, Dalen I, Bergsland N, Zivadinov R, Alves G, Myhr KM, Farbu E. CSF neurofilament light chain predicts 10-year clinical and radiologic worsening in multiple sclerosis. Mult Scler J Exp Transl Clin. 2021 Dec 6;7(4):20552173211060337. doi: 10.1177/20552173211060337. eCollection 2021 Oct.

PMID: 34900328

  1. Gonzalez MC, Ashton NJ, Gomes BF, Tovar-Rios DA, Blanc F, Karikari TK, Mollenhauer B, Pilotto A, Lemstra A, Paquet C, Abdelnour C, Kramberger MG, Bonanni L, Vandenberghe R, Hye A, Blennow K, Zetterberg H, Aarsland D; European–Dementia With Lewy Bodies (E-DLB) Consortium. Association of Plasma p-tau181 and p-tau231 Concentrations With Cognitive Decline in Patients With Probable Dementia With Lewy Bodies.

JAMA Neurol. 2022 Jan 1;79(1):32-37. doi: 10.1001/jamaneurol.2021.4222.

PMID: 34807233

  1. Lauvsnes MB, Zetterberg H, Blennow K, Kvaløy JT, Tjensvoll AB, Maroni S, Beyer MK, Greve OJ, Kvivik I, Alves G, Gøransson LG, Harboe E, Hirohata S, Omdal R. Neurofilament light in plasma is a potential biomarker of central nervous system involvement in systemic lupus erythematosus. J Neurol. 2021 Nov 20. doi: 10.1007/s00415-021-10893-z. Online ahead of print.

PMID: 34800169

  1. Green S, Perrott SL, McCleary A, Sleeman I, Maple-Grødem J, Counsell CE, Macleod AD. First delirium episode in Parkinson's disease and parkinsonism: incidence, predictors, and outcomes. NPJ Parkinsons Dis. 2021 Oct 11;7(1):92. doi: 10.1038/s41531-021-00234-2.

PMID: 34635668

  1. Chung J, Ushakova A, Doitsidou M, Tzoulis C, Tysnes OB, Dalen I, Pedersen KF, Alves G, Maple-Grødem J. The impact of common genetic variants in cognitive decline in the first seven years of Parkinson's disease: A longitudinal observational study. Neurosci Lett. 2021 Nov 1;764:136243. doi: 10.1016/j.neulet.2021.136243. Epub 2021 Sep 10.

PMID: 34509566

  1. Hiorth YH, Alves G, Nilsson MH. Parkinsons sjukdom. In: FYSS 2021 - Fysisk aktivitet i sjukdomsprevention och sjukdomsbehandling. Läkartidningen Førlag, Sweden 2021.
  2. Hetland J, Braatveit KJ, Hagen E, Lundervold AJ, Erga AH. Prevalence and Characteristics of Borderline Intellectual Functioning in a Cohort of Patients With Polysubstance Use Disorder. Front Psychiatry. 2021 Jul 14;12:651028. doi: 10.3389/fpsyt.2021.651028. eCollection 2021.

PMID: 34335320

  1. Pedersen CC, Lange J, Førland MGG, Macleod AD, Alves G, Maple-Grødem J. A systematic review of associations between common SNCA variants and clinical heterogeneity in Parkinson's disease. NPJ Parkinsons Dis. 2021 Jul 1;7(1):54. doi: 10.1038/s41531-021-00196-5.

PMID: 34210990

  1. Rajkumar AP, Hye A, Lange J, Manesh YR, Ballard C, Fladby T, Aarsland D. Next-Generation RNA-Sequencing of Serum Small Extracellular Vesicles Discovers Potential Diagnostic Biomarkers for Dementia With Lewy Bodies. Am J Geriatr Psychiatry. 2021 Jun;29(6):573-584. doi: 10.1016/j.jagp.2020.10.012. Epub 2020 Oct 27.

PMID: 33160816

  1. Liu G, Peng J, Liao Z, Locascio JJ, Corvol JC, Zhu F, Dong X, Maple-Grødem J, Campbell MC, Elbaz A, Lesage S, Brice A, Mangone G, Growdon JH, Hung AY, Schwarzschild MA, Hayes MT, Wills AM, Herrington TM, Ravina B, Shoulson I, Taba P, Kõks S, Beach TG, Cormier-Dequaire F, Alves G, Tysnes OB, Perlmutter JS, Heutink P, Amr SS, van Hilten JJ, Kasten M, Mollenhauer B, Trenkwalder C, Klein C, Barker RA, Williams-Gray CH, Marinus J; International Genetics of Parkinson Disease Progression (IGPP) Consortium, Scherzer CR. Genome-wide survival study identifies a novel synaptic locus and polygenic score for cognitive progression in Parkinson's disease. Nat Genet. 2021 Jun;53(6):787-793. doi: 10.1038/s41588-021-00847-6. Epub 2021 May 6.

PMID: 33958783

  1. Ongre SO, Dalen I, Tysnes OB, Alves G, Herlofson K. Letter to the editor in response to the letter from the EPIPARK Study Group regarding the publication 'Progression of fatigue in Parkinson's disease - a 9-year follow-up' (Eur J Neurol 2021. doi:10.1111/ene.14520). Eur J Neurol. 2021 Jun;28(6):e33-e34. doi: 10.1111/ene.14765. Epub 2021 Feb 23. PMID: 33547699
  2. Camacho M, Macleod AD, Maple-Grødem J, Evans JR, Breen DP, Cummins G, Wijeyekoon RS, Greenland JC, Alves G, Tysnes OB, Lawson RA, Barker RA, Williams-Gray CH. Early constipation predicts faster dementia onset in Parkinson's disease. NPJ Parkinsons Dis. 2021 May 26;7(1):45. doi: 10.1038/s41531-021-00191-w.

PMID: 34039994

  1. Toker L, Tran GT, Sundaresan J, Tysnes OB, Alves G, Haugarvoll K, Nido GS, Dölle C, Tzoulis C. Genome-wide histone acetylation analysis reveals altered transcriptional regulation in the Parkinson's disease brain. Mol Neurodegener. 2021 May 5;16(1):31. doi: 10.1186/s13024-021-00450-7.

PMID: 33947435

  1. Borda MG, Ayala Copete AM, Tovar-Rios DA, Jaramillo-Jimenez A, Giil LM, Soennesyn H, Gómez-Arteaga C, Venegas-Sanabria LC, Kristiansen I, Chavarro-Carvajal DA, Caicedo S, Cano-Gutierrez CA, Vik-Mo A, Aarsland D. Association of Malnutrition with Functional and Cognitive Trajectories in People Living with Dementia: A Five-Year Follow-Up Study. J Alzheimers Dis. 2021;79(4):1713-1722. doi: 10.3233/JAD-200961.

PMID: 33459715

  1. Maple-Grødem J, Dalen I, Tysnes OB, Macleod AD, Forsgren L, Counsell CE, Alves G. Association of GBA Genotype With Motor and Functional Decline in Patients With Newly Diagnosed Parkinson Disease. Neurology. 2021 Feb 16;96(7):e1036-e1044. doi: 10.1212/WNL.0000000000011411. Epub 2020 Dec 21.

PMID: 33443131

  1. Szwedo AA, Pedersen CC, Ushakova A, Forsgren L, Tysnes OB, Counsell CE, Alves G, Lange J, Macleod AD, Maple-Grødem J. Association of SNCA Parkinson's Disease Risk Polymorphisms With Disease Progression in Newly Diagnosed Patients. Front Neurol. 2021 Feb 10;11:620585. doi: 10.3389/fneur.2020.620585. eCollection 2020.

PMID: 33643180

  1. Maple-Grødem J, Paul KC, Dalen I, Ngo KJ, Wong D, Macleod AD, Counsell CE, Bäckström D, Forsgren L, Tysnes OB, Kusters CDJ, Fogel BL, Bronstein JM, Ritz B, Alves G. Lack of Association Between GBA Mutations and Motor Complications in European and American Parkinson's Disease Cohorts. J Parkinsons Dis. 2021;11(4):1569-1578. doi: 10.3233/JPD-212657.

PMID: 34275908

  1. Oftedal L, Maple-Grødem J, Førland MGG, Alves G, Lange J. Validation and assessment of preanalytical factors of a fluorometric in vitro assay for glucocerebrosidase activity in human cerebrospinal fluid. Sci Rep. 2020 Dec 16;10(1):22098. doi: 10.1038/s41598-020-79104-5.

PMID: 33328543

  1. Dick F, Nido GS, Alves GW, Tysnes OB, Nilsen GH, Dölle C, Tzoulis C. Differential transcript usage in the Parkinson's disease brain. PLoS Genet. 2020 Nov 2;16(11):e1009182. doi: 10.1371/journal.pgen.1009182. eCollection 2020 Nov.

PMID: 33137089

  1. Tjensvoll AB, Lauvsnes MB, Zetterberg H, Kvaløy JT, Kvivik I, Maroni SS, Greve OJ, Beyer MK, Hirohata S, Putterman C, Alves G, Harboe E, Blennow K, Gøransson LG, Omdal R. Neurofilament light is a biomarker of brain involvement in lupus and primary Sjögren's syndrome. J Neurol. 2020 Oct 30. doi: 10.1007/s00415-020-10290-y. Online ahead of print.

PMID: 33128084

  1. Iwaki H, Blauwendraat C, Leonard HL, Makarious MB, Kim JJ, Liu G, Maple-Grødem J, Corvol JC, Pihlstrøm L, van Nimwegen M, Smolensky L, Amondikar N, Hutten SJ, Frasier M, Nguyen KH, Rick J, Eberly S, Faghri F, Auinger P, Scott KM, Wijeyekoon R, Van Deerlin VM, Hernandez DG, Gibbs RJ, Day-Williams AG, Brice A, Alves G, Noyce AJ, Tysnes OB, Evans JR, Breen DP, Estrada K, Wegel CE, Danjou F, Simon DK, Andreassen OA, Ravina B, Toft M, Heutink P, Bloem BR, Weintraub D, Barker RA, Williams-Gray CH, van de Warrenburg BP, Van Hilten JJ, Scherzer CR, Singleton AB, Nalls MA. Differences in the Presentation and Progression of Parkinson's Disease by Sex.

Mov Disord. 2020 Oct 1. doi: 10.1002/mds.28312. Online ahead of print

PMID: 33002231

  1. Gaare JJ, Nido G, Dölle C, Sztromwasser P, Alves G, Tysnes OB, Haugarvoll K, Tzoulis C. Meta-analysis of whole-exome sequencing data from two independent cohorts finds no evidence for rare variant enrichment in Parkinson disease associated loci. PLoS One. 2020 Oct 1;15(10):e0239824. doi: 10.1371/journal.pone.0239824. eCollection 2020.

PMID: 33002040

  1. Jakubec M, Maple-Grødem J, Akbari S, Nesse S, Halskau Ø, Mork-Jansson AE. Plasma-derived exosome-like vesicles are enriched in lyso-phospholipids and pass the blood-brain barrier. PLoS One. 2020 Sep 21;15(9):e0232442. doi: 10.1371/journal.pone.0232442. eCollection 2020.

PMID: 32956358

  1. de Grahl I, Rout SS, Maple-Grødem J, Reumann S. Development of a constitutive and an auto-inducible high-yield expression system for recombinant protein production in the microalga Nannochloropsis oceanica. Appl Microbiol Biotechnol. 2020 Oct;104(20):8747-8760. doi: 10.1007/s00253-020-10789-4. Epub 2020 Sep 9.

PMID: 32902683

  1. Ongre SO, Dalen I, Tysnes OB, Alves G, Herlofson K. Progression of fatigue in Parkinson's disease -A nine-year follow-up. Eur J Neurol. 2020 Sep 13. doi: 10.1111/ene.14520. Online ahead of print.

PMID: 32920893

  1. Kusters CDJ, Paul KC, Duarte Folle A, Keener AM, Bronstein JM, Dobricic V, Tysnes OB, Bertram L, Alves G, Sinsheimer JS, Lill CM, Maple-Grødem J, Ritz BR. Genetic risk scores and hallucinations in patients with Parkinson disease. Neurol Genet. 2020 Jul 20;6(5):e492. doi: 10.1212/NXG.0000000000000492. eCollection 2020 Oct.

PMID: 32802953

  1. Borda MG, Aarsland D, Tovar-Rios DA, Giil LM, Ballard C, Gonzalez MC, Brønnick K, Alves G, Oppedal K, Soennesyn H, Vik-Mo AO. Neuropsychiatric Symptoms and Functional Decline in Alzheimer's Disease and Lewy Body Dementia. J Am Geriatr Soc. 2020 Aug 1. doi: 10.1111/jgs.16709. Online ahead of print.

PMID: 32738062

  1. Erga AH, Alves G, Tysnes OB, Pedersen KF. Impulsive and compulsive behaviors in Parkinson's disease: Impact on quality of and satisfaction with life, and caregiver burden. Parkinsonism Relat Disord. 2020 Jul 9;78:27-30. doi: 10.1016/j.parkreldis.2020.07.007. Online ahead of print.

PMID: 32679528

  1. Ramsay N, Macleod AD, Alves G, Camacho M, Forsgren L, Lawson RA, Maple-Grødem J, Tysnes OB, Williams-Gray CH, Yarnall AJ, Counsel. Validation of a UPDRS-/MDS-UPDRS-based definition of functional dependency for Parkinson's disease. Park Rel Disord 2020 May 30. doi: 10.1016/j.parkreldis.2020.05.034. Online ahead of print.

PMID: 32645619

  1. Radder DLM, Nonnekes J, van Nimwegen M, Eggers C, Abbruzzese G, Alves G, Browner N, Chaudhuri KR, Ebersbach G, Ferreira JJ, Fleisher JE, Fletcher P, Frazzitta G, Giladi N, Guttman M, Iansek R, Khandhar S, Klucken J, Lafontaine AL, Marras C, Nutt J, Okun MS, Parashos SA, Munneke M, Bloem BR. Recommendations for the Organization of Multidisciplinary Clinical Care Teams in Parkinson's Disease. J Parkinsons Dis. 2020 May 16. doi: 10.3233/JPD-202078. Online ahead of print.

PMID: 32444563

  1. Nido GS, Dick F, Toker L, Petersen K, Alves G, Tysnes OB, Jonassen I, Haugarvoll K, Tzoulis C. Common gene expression signatures in Parkinson's disease are driven by changes in cell composition. Acta Neuropathol Commun. 2020 Apr 21;8(1):55.

PMID: 32317022

  1. Erga AH, Alves G, Tysnes OB, Pedersen KF. Evolution of impulsive-compulsive behaviors and cognition in Parkinson's disease. J Neurol. 2020 Jan;267(1):259-266.

PMID: 31628533

  1. Hiorth YH, Pedersen KF, Dalen I, Tysnes OB, Alves G. Orthostatic hypotension in Parkinson disease: A 7-year prospective population-based study. Neurology. 2019 Oct 15;93(16):e1526-e1534.

PMID: 31527282

  1. Iwaki H, Blauwendraat C, Leonard HL, Kim JJ, Liu G, Maple-Grødem J, Corvol JC, Pihlstrøm L, van Nimwegen M, Hutten SJ, Nguyen KH, Rick J, Eberly S, Faghri F, Auinger P, Scott KM, Wijeyekoon R, Van Deerlin VM, Hernandez DG, Gibbs JR; International Parkinson's Disease Genomics Consortium, Chitrala KN, Day-Williams AG, Brice A, Alves G, Noyce AJ, Tysnes OB, Evans JR, Breen DP, Estrada K, Wegel CE, Danjou F, Simon DK, Andreassen O, Ravina B, Toft M, Heutink P, Bloem BR, Weintraub D, Barker RA, Williams-Gray CH, van de Warrenburg BP, Van Hilten JJ, Scherzer CR, Singleton AB, Nalls MA. Genomewide association study of Parkinson's disease clinical biomarkers in 12 longitudinal patients' cohorts. Mov Disord. 2019 Dec;34(12):1839-1850.

PMID: 31505070

  1. Iwaki H, Blauwendraat C, Leonard HL, Liu G, Maple-Grødem J, Corvol JC, Pihlstrøm L, van Nimwegen M, Hutten SJ, Nguyen KH, Rick J, Eberly S, Faghri F, Auinger P, Scott KM, Wijeyekoon R, Van Deerlin VM, Hernandez DG, Day-Williams AG, Brice A, Alves G, Noyce AJ, Tysnes OB, Evans JR, Breen DP, Estrada K, Wegel CE, Danjou F, Simon DK, Ravina B, Toft M, Heutink P, Bloem BR, Weintraub D, Barker RA, Williams-Gray CH, van de Warrenburg BP, Van Hilten JJ, Scherzer CR, Singleton AB, Nalls MA. Genetic risk of Parkinson disease and progression: An analysis of 13 longitudinal cohorts. Neurol Genet. 2019 Jul 9;5(4):e348.

PMID: 31404238

  1. Førland MG, Tysnes OB, Aarsland D, Maple-Grødem J, Pedersen KF, Alves G, Lange J. The value of cerebrospinal fluid α-synuclein and the tau/α-synuclein ratio for diagnosis of neurodegenerative disorders with Lewy pathology. Eur J Neurol. 2020 Jan;27(1):43-50.

PMID: 31293044

  1. Solvang SH, Nordrehaug JE, Aarsland D, Lange J, Ueland PM, McCann A, Midttun Ø, Tell GS, Giil LM.

Kynurenines, Neuropsychiatric Symptoms, and Cognitive Prognosis in Patients with Mild Dementia. Int J Tryptophan Res. 2019 Sep 29;12:1178646919877883. doi: 10.1177/1178646919877883. eCollection 2019.

PMID: 31632053

  1. Ghanavatinejad F, Fard Tabrizi ZP, Omidghaemi S, Sharifi E, Møller SG, Jami MS. Protein biomarkers of neural system. J Otol. 2019 Sep;14(3):77-88. doi: 10.1016/j.joto.2019.03.001. Epub 2019 Mar 23.

PMID: 31467504

  1. Eichler W, Lohrenz A, Simon KU, Krohn S, Lange J, Bürger S, Liebscher I. The role of ADGRE5/CD97 in human retinal pigment epithelial cell growth and survival. Ann N Y Acad Sci. 2019 Nov;1456(1):64-79. doi: 10.1111/nyas.14210. Epub 2019 Aug 9.

PMID: 31397926

  1. Bjornestad J, Svendsen TS, Slyngstad TE, Erga AH, McKay JR, Nesvåg S, Skaalevik AW, Veseth M, Moltu C.

"A Life More Ordinary" Processes of 5-Year Recovery From Substance Abuse. Experiences of 30 Recovered Service Users. Front Psychiatry. 2019 Sep 18;10:689. doi: 10.3389/fpsyt.2019.00689. eCollection 2019.

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  1. Kurtishi A, Rosen B, Patil KS, Alves GW, Møller SG. Cellular Proteostasis in Neurodegeneration. Mol Neurobiol. 2019 May;56(5):3676-3689.

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  1. Hagen E, Sømhovd M, Hesse M, Arnevik EA, Erga AH. Measuring cognitive impairment in young adults with polysubstance use disorder with MoCA or BRIEF-A - The significance of psychiatric symptoms. J Subst Abuse Treat. 2019 Feb;97:21-27. doi: 10.1016/j.jsat.2018.11.010. Epub 2018 Nov 22.

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  1. Gjerde KV, Müller B, Skeie GO, Assmus J, Alves G, Tysnes OB. Hyposmia in a simple smell test is associated with accelerated cognitive decline in early Parkinson's disease. Acta Neurol Scand 2018;138(6):508-514

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  1. Herlofson K, Heijnen CJ, Lange J, Alves G, Tysnes OB, Friedman JH, Fagundes CP. Inflammation and fatigue in early, untreated Parkinson's Disease. Acta Neurol Scand. 2018;138(5):394-399.

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  1. Molde H, Moussavi Y, Kopperud ST, Erga AH, Hansen AL, Pallesen S. Impulse-Control Disorders in Parkinson's Disease: A Meta-Analysis and Review of Case-Control Studies. Front Neurol. 2018 May 22;9:330. doi: 10.3389/fneur.2018.00330. eCollection 2018.

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  1. Lunde KA, Chung J, Dalen I, Pedersen KF, Linder J, Domellöf ME, Elgh E, Macleod AD, Tzoulis C, Larsen JP, Tysnes OB, Forsgren L, Counsell CE, Alves G, Maple-Grødem J. Association of glucocerebrosidase polymorphisms andmutations with dementia in incident Parkinson's disease. Alzheimers Dement 2018; 14(10):1293-1301.

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  1. Erga AH, Bjørnestad A, Tysnes OB, Alves G, Pedersen KF. Is psychosis associated with impulse control disorders in Parkinson's disease? Park Relat Disord 2018; 53:110-111.

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  1. Maple-Grødem J, Chung J, Lunde KA, Tzoulis C, Tysnes OB, Pedersen KF, Alves G. Alzheimer disease associated variants in SORL1 accelerate dementia development in Parkinson disease. Neurosci Lett 2018;674:123-126.

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  1. Erga AH, Dalen I, Ushakova A, Chung J, Tzoulis C, Tysnes OB, Alves G, Pedersen KF, Maple-Grødem J. Dopaminergic and Opioid Pathways Associated with Impulse Control Disorders in Parkinson's Disease. Front Neurol 2018;9:109. doi: 10.3389/fneur.2018.00109.

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  1. Oltedal S, Skaland I, Maple-Grødem J, Tjensvoll K, Janssen EAM, Gilje B, Smaaland R, Heikkilä R, Nordgård O.

Expression profiling and intracellular localization studies of the novel Proline-, Histidine-, and Glycine-rich protein 1 suggest an essential role in gastro-intestinal epithelium and a potential clinical application in colorectal cancer diagnostics. BMC Gastroenterol. 2018 Feb 7;18(1):26. doi: 10.1186/s12876-018-0752-8.

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  1. Førland MG, Öhrfelt A, Dalen I, Tysnes OB, Blennow K, Zetterberg H, Pedersen KF, Alves G, Lange J. Evolution of cerebrospinal fluid total α-synuclein in Parkinson's disease. Park Relat Disord 2018;49:4-8.

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  1. Gaare JJ, Nido GS, Sztromwasser P, Knappskog PM, Dahl O, Lund-Johansen M, Alves G, Tysnes OB, Johansson S, Haugarvoll K, Tzoulis C. No evidence for rare TRAP1 mutations influencing the risk of idiopathic Parkinson's disease. Brain. 2018 Mar 1;141(3):e16.

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  1. Piston D, Alvarez-Erviti L, Bansal V, Gargano D, Yao Z, Szabadkai G, Odell M, Puno MR, Björkblom B, Maple-Grødem J, Breuer P, Kaut O, Larsen JP, Bonn S, Møller SG, Wüllner U, Schapira AHV, Gegg ME. DJ-1 is a redox sensitive adapter protein for high molecular weight complexes involved in regulation of catecholamine homeostasis.

Hum Mol Genet. 2018 Feb 1;27(3):576. doi: 10.1093/hmg/ddx425.

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  1. Flønes IH, Fernandez-Vizarra E, Lykouri M, Brakedal B, Skeie GO, Miletic H, Lilleng PK, Alves G, Tysnes OB, Haugarvoll K, Dölle C, Zeviani M, Tzoulis C. Neuronal complex I deficiency occurs throughout the Parkinson's disease brain, but is not associated with neurodegeneration or mitochondrial DNA damage. Acta Neuropathol 2018;135:409-425.

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  1. Nido GS, Dölle C, Flønes I, Tuppen HA, Alves G, Tysnes OB, Haugarvoll K, Tzoulis C. Ultradeep mapping of neuronal mitochondrial deletions in Parkinson's disease. Neurobiol Aging. 2018;63:120-127.

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  1. Hagen E, Erga AH, Nesvåg SM, McKay JR, Lundervold AJ, Walderhaug E. One-year abstinence improves ADHD symptoms among patients with polysubstance use disorder. Addict Behav Rep. 2017 Sep 4;6:96-101. doi: 10.1016/j.abrep.2017.08.005. eCollection 2017 Dec.

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  1. Larsen JP, Dalen I, Pedersen KF, Tysnes OB. The natural history of depressive symptoms in patients with incident Parkinson's disease: a prospective cohort study. J Neurol. 2017 Dec;264(12):2401-2408. doi: 10.1007/s00415-017-8638-1. Epub 2017 Oct 14.

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  1. Piston D, Alvarez-Erviti L, Bansal V, Gargano D, Yao Z, Szabadkai G, Odell M, Puno MR, Björkblom B, Maple-Grødem J, Breuer P, Kaut O, Larsen JP, Bonn S, Møller SG, Wüllner U, Schapira AHV, Gegg ME. DJ-1 is a redox sensitive adapter protein for high molecular weight complexes involved in regulation of catecholamine homeostasis.

Hum Mol Genet. 2017 Oct 15;26(20):4028-4041. doi: 10.1093/hmg/ddx294.

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  1. Macleod AD, Dalen I, Tysnes OB, Larsen JP, Counsell CE. Development and validation of prognostic survival models in newly diagnosed Parkinson's disease. Mov Disord. 2018 Jan;33(1):108-116. doi: 10.1002/mds.27177. Epub 2017 Oct 4.

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  1. Chwiszczuk L, Breitve MH, Brønnick K, Gjerstad MD, Hynninen M, Aarsland D, Rongve A. REM Sleep Behavior Disorder Is Not Associated with a More Rapid Cognitive Decline in Mild Dementia. Front Neurol. 2017 Aug 7;8:375. doi: 10.3389/fneur.2017.00375. eCollection 2017.

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  1. Ali MR, Sadoqi M, Møller SG, Boutajangout A, Mezei M. Assessing the binding of cholinesterase inhibitors by docking and molecular dynamics studies. J Mol Graph Model. 2017 Sep;76:36-42. doi: 10.1016/j.jmgm.2017.06.027. Epub 2017 Jun 29.

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  1. Ahmadinejad F, Geir Møller S, Hashemzadeh-Chaleshtori M, Bidkhori G, Jami MS. Molecular Mechanisms behind Free Radical Scavengers Function against Oxidative Stress. Antioxidants (Basel). 2017 Jul 10;6(3):51. doi: 10.3390/antiox6030051.

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  1. Bjornestad A, Pedersen KF, Tysnes OB, Alves G. Clinical milestones in Parkinson's disease: A 7-year population-based incident cohort study. Parkinsonism Relat Disord 2017;42:28-33.

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  1. Kluger BM, Pedersen KF, Tysnes OB, Ongre SO, Øygarden B, Herlofson K. Is fatigue associated with cognitive dysfunction in early Parkinson's disease? Parkinsonism Relat Disord. 2017 Apr;37:87-91. doi: 10.1016/j.parkreldis.2017.02.005. Epub 2017 Feb 7.

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  1. Alves G, Bonanni L. Neurofilament light: A heavyweight diagnostic biomarker in neurodegenerative parkinsonism? Neurology 2017;88:922-923.

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  1. Hagen E, Erga AH, Hagen KP, Nesvåg SM, McKay JR, Lundervold AJ, Walderhaug E. One-year sobriety improves satisfaction with life, executive functions and psychological distress among patients with polysubstance use disorder.

J Subst Abuse Treat. 2017 May;76:81-87. doi: 10.1016/j.jsat.2017.01.016. Epub 2017 Jan 31.

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  1. Pedersen KF, Larsen JP, Tysnes OB, Alves G. Natural course of mild cognitive impairment in Parkinson disease: A 5-year population-based study. Neurology 2017;88:767-774.

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  1. Hiorth YH, Alves G, Larsen JP, Schulz J, Tysnes OB, Pedersen KF. Long-term risk of falls in an incident Parkinson's disease cohort: the Norwegian ParkWest study. J Neurol 2017;264:364-372.

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  1. Tholfsen LK, Larsen JP, Schulz J, Tysnes OB, Gjerstad MD. Changes in insomnia subtypes in early Parkinson disease.

Neurology. 2017 Jan 24;88(4):352-358. doi: 10.1212/WNL.0000000000003540. Epub 2016 Dec 16.

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  1. Erga AH, Alves G, Larsen JP, Tysnes OB, Pedersen KF. Impulsive and Compulsive Behaviors in Parkinson's Disease: The Norwegian ParkWest Study. J Parkinsons Dis 2017;7:183-191.

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  1. Dölle C, Flønes I, Nido GS, Miletic H, Osuagwu N, Kristoffersen S, Lilleng PK, Larsen JP, Tysnes OB, Haugarvoll K, Bindoff LA, Tzoulis C. Defective mitochondrial DNA homeostasis in the substantia nigra in Parkinson disease.Nat Commun. 2016 Nov 22;7:13548. doi: 10.1038/ncomms13548.

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  1. Gaare JJ, Skeie GO, Tzoulis C, Larsen JP, Tysnes OB. Familial aggregation of Parkinson's disease may affect progression of motor symptoms and dementia. Mov Disord. 2017 Feb;32(2):241-245. doi: 10.1002/mds.26856. Epub 2016 Nov 10.

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  1. Abdullah R, Patil KS, Rosen B, Pal R, Prabhudesai S, Lee S, Basak I, Hoedt E, Yang P, Panick K, Ho HP, Chang E, Tzoulis C, Larsen JP, Neubert TA, Alves G, Møller SG. Subcellular Parkinson's Disease-Specific Alpha-Synuclein Species Show Altered Behavior in Neurodegeneration. Mol Neurobiol 2016;54:7639-7655.

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  1. Løvereide L, Hagell P. Measuring Life Satisfaction in Parkinson's Disease and Healthy Controls Using the Satisfaction With Life Scale. PLoS One. 2016 Oct 24;11(10):e0163931. doi: 10.1371/journal.pone.0163931. eCollection 2016.

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  1. Ongre SO, Larsen JP, Tysnes OB, Herlofson K. Fatigue in early Parkinson's disease: the Norwegian ParkWest study. Eur J Neurol. 2017 Jan;24(1):105-111. doi: 10.1111/ene.13161. Epub 2016 Sep 26.

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  1. Wei X, Yan R, Chen Z, Weng R, Liu X, Gao H, Xu X, Kang Z, Liu Z, Guo Y, Liu Z, Larsen JP, Wang J, Tang B, Hallett M, Wang Q. Combined Diffusion Tensor Imaging and Arterial Spin Labeling as Markers of Early Parkinson's disease.Sci Rep. 2016 Sep 20;6:33762. doi: 10.1038/srep33762.

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  1. Bjornestad A, Tysnes OB, Larsen JP, Alves G. Loss of independence in early Parkinson disease: A 5-year population-based incident cohort study. Neurology 2016;87:1599-1606.

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  1. Førland MG, Öhrfelt A, Oftedal LS, Tysnes OB, Larsen JP, Blennow K, Zetterberg H, Alves G, Lange J. Validation of a new assay for α-synuclein detection in cerebrospinal fluid. Clin Chem Lab Med 2017;55:254-260.

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  1. Heinzel S, Roeben B, Ben-Shlomo Y, Lerche S, Alves G, Barone P, Behnke S, Berendse HW, Bloem BR, Burn D, Dodel R, Grosset DG, Hu M, Kasten M, Krüger R, Moccia M, Mollenhauer B, Oertel W, Suenkel U, Walter U, Wirdefeldt K, Liepelt-Scarfone I, Maetzler W, Berg D. Prodromal markers in Parkinson's disease: Limitations in longitudinal studies and lessons learned. Front Aging Neurosci 2016;8:147. doi: 10.3389/fnagi.2016.00147.

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  1. Lerche S, Heinzel S, Alves GW, Barone P, Behnke S, Ben-Shlomo Y, Berendse H, Bloem BR, Burn D, Dodel R, Grosset DG, Hipp G, Hu MT, Kasten M, Krüger R, Liepelt-Scarfone I, Maetzler W, Moccia M, Mollenhauer B, Oertel W, Roeben B, Walter U, Wirdefeldt K, Berg D. Aiming for study comparability in Parkinson's disease: Proposal for a modular set of biomarker assessments to be used in longitudinal studies. Front Aging Neurosci 2016;8:121. doi: 10.3389/fnagi.2016.00121.

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  1. Prabhudesai S, Bensabeur FZ, Abdullah R, Basak I, Baez S, Alves G, Holtzman NG, Larsen JP, Møller SG. LRRK2 knockdown in zebrafish causes developmental defects, neuronal loss, and synuclein aggregation. J Neurosci Res 2016;94:17-35.

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  1. Bjornestad A, Tysnes OB, Larsen JP, Alves G. Reliability of three disability scales for detection of independence loss in Parkinson’s disease. Parkinson’s Disease 2016; 2016:1941034. doi: 1155/2016/1941034.

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  1. Hagen E, Erga AH, Hagen KP, Nesvåg SM, McKay JR, Lundervold AJ, Walderhaug E.Assessment of Executive Function in Patients With Substance Use Disorder: A Comparison of Inventory- and Performance-Based Assessment.

J Subst Abuse Treat. 2016 Jul;66:1-8. doi: 10.1016/j.jsat.2016.02.010. Epub 2016 Mar 9.

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  1. Lange J, Lunde KA, Sletten C, Møller SG, Tysnes OB, Alves G, Larsen JP, Maple-Grødem J. Association of a BACE1 Gene Polymorphism with Parkinson's Disease in a Norwegian Population. Parkinsons Dis. 2015;2015:973298. doi: 10.1155/2015/973298. Epub 2015 Dec 14.

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  1. Mathisen SM, Dalen I, Larsen JP, Kurz M. Long-Term Mortality and Its Risk Factors in Stroke Survivors. J Stroke Cerebrovasc Dis. 2016 Mar;25(3):635-41. doi: 10.1016/j.jstrokecerebrovasdis.2015.11.039. Epub 2015 Dec 28.

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  1. Hiorth YH, Larsen JP, Lode K, Tysnes OB, Godfrey A, Lord S, Rochester L, Pedersen KF. Impact of Falls on Physical Activity in People with Parkinson's Disease.J Parkinsons Dis. 2016;6(1):175-82. doi: 10.3233/JPD-150640.

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  1. Basak I, Patil KS, Alves G, Larsen JP, Møller SG. microRNAs as neuroregulators, biomarkers and therapeutic agents in neurodegenerative diseases. Cell Mol Life Sci 2016;73:811-27.
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  2. Bjornestad A, Forsaa EB, Pedersen KF, Tysnes OB, Larsen JP, Alves G. Risk and course of motor complications in a population-based incident Parkinson's disease cohort. Parkinsonism Relat Disord 2016;22:48-53.

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  1. Andersen K, Baardsen R, Dalen I, Larsen JP. Recurrent and Transient Spinal Pain Among Commercial Helicopter Pilots. Aerosp Med Hum Perform. 2015 Nov;86(11):962-9. doi: 10.3357/AMHP.4237.2015.

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  1. Chwiszczuk L, Breitve M, Hynninen M, Gjerstad MD, Aarsland D, Rongve A. Higher Frequency and Complexity of Sleep Disturbances in Dementia with Lewy Bodies as Compared to Alzheimer's Disease. Neurodegener Dis. 2016;16(3-4):152-60. doi: 10.1159/000439252. Epub 2015 Nov 10.

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  1. Malmqvist S, Kjaermann I, Andersen K, Økland I, Larsen JP, Brønnick K. The association between pelvic girdle pain and sick leave during pregnancy; a retrospective study of a Norwegian population.BMC Pregnancy Childbirth. 2015 Oct 5;15:237. doi: 10.1186/s12884-015-0667-0.

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  1. Pal R, Larsen JP, Moller SG. The Potential of Proteomics in Understanding Neurodegeneration.Int Rev Neurobiol. 2015;121:25-58. doi: 10.1016/bs.irn.2015.05.002. Epub 2015 Jun 19.

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  1. Jami MS, Salehi-Najafabadi Z, Ahmadinejad F, Hoedt E, Chaleshtori MH, Ghatrehsamani M, Neubert TA, Larsen JP, Møller SG. Edaravone leads to proteome changes indicative of neuronal cell protection in response to oxidative stress.

Neurochem Int. 2015 Nov;90:134-41. doi: 10.1016/j.neuint.2015.07.024. Epub 2015 Jul 29.

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  1. Patil KS, Basak I, Pal R, Ho HP, Alves G, Chang EJ, Larsen JP, Møller SG. A Proteomics Approach to Investigate miR-153-3p and miR-205-5p Targets in Neuroblastoma Cells. PLoS One 2015;10(12):e0143969.
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  2. Lerche S, Liepelt-Scarfone I, Alves G, Barone P, Behnke S, Ben-Shlomo Y, Berendse H, Burn D, Dodel R, Grosset D, Heinzel S, Hu M, Kasten M, Krüger R, Maetzler W, Moccia M, Mollenhauer B, Oertel W, Roeben B, Sünkel U, Walter U, Wirdefeldt K, Berg D. Methods in neuroepidemiology. Characterization of european longitudinal cohort studies in Parkinson's disease - report of the JPND working group BioLoC-PD. Neuroepidemiology 2015;45:282-97.
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  3. Linster E, Stephan I, Bienvenut WV, Maple-Grødem J, Myklebust LM, Huber M, Reichelt M, Sticht C, Møller SG, Meinnel T, Arnesen T, Giglione C, Hell R, Wirtz M. Downregulation of N-terminal acetylation triggers ABA-mediated drought responses in Arabidopsis. Nat Commun. 2015 Jul 17;6:7640. doi: 10.1038/ncomms8640.

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  1. Development of excessive daytime sleepiness in early Parkinson disease.Tholfsen LK, Larsen JP, Schulz J, Tysnes OB, Gjerstad MD. Neurology. 2015 Jul 14;85(2):162-8. doi: 10.1212/WNL.0000000000001737. Epub 2015 Jun 17.

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  1. Lill CM, Rengmark A, Pihlstrøm L, Fogh I, Shatunov A, Sleiman PM, Wang LS, Liu T, Lassen CF, Meissner E, Alexopoulos P, Calvo A, Chio A, Dizdar N, Faltraco F, Forsgren L, Kirchheiner J, Kurz A, Larsen JP, Liebsch M, Linder J, Morrison KE, Nissbrandt H, Otto M, Pahnke J, Partch A, Restagno G, Rujescu D, Schnack C, Shaw CE, Shaw PJ, Tumani H, Tysnes OB, Valladares O, Silani V, van den Berg LH, van Rheenen W, Veldink JH, Lindenberger U, Steinhagen-Thiessen E; SLAGEN Consortium; Teipel S, Perneczky R, Hakonarson H, Hampel H, von Arnim CAF, Olsen JH, Van Deerlin VM, Al-Chalabi A, Toft M, Ritz B, Bertram L. The role of TREM2 R47H as a risk factor for Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and Parkinson's disease. Alzheimers Dement. 2015 Dec;11(12):1407-1416. doi: 10.1016/j.jalz.2014.12.009. Epub 2015 Apr 30.

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  1. Gausel AM, Kjærmann I, Malmqvist S, Dalen I, Larsen JP, Økland I. Pelvic girdle pain 3-6 months after delivery in an unselected cohort of Norwegian women.Eur Spine J. 2016 Jun;25(6):1953-9. doi: 10.1007/s00586-015-3959-1. Epub 2015 Apr 22.

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  1. Pihlstrøm L, Rengmark A, Bjørnarå KA, Dizdar N, Fardell C, Forsgren L, Holmberg B, Larsen JP, Linder J, Nissbrandt H, Tysnes OB, Dietrichs E, Toft M. Fine mapping and resequencing of the PARK16 locus in Parkinson's disease.J Hum Genet. 2015 Jul;60(7):357-62. doi: 10.1038/jhg.2015.34. Epub 2015 Apr 9.

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  1. Tzoulis C, Zayats T, Knappskog PM, Müller B, Larsen JP, Tysnes OB, Bindoff LA, Johansson S, Haugarvoll K. HTRA2 p.G399S in Parkinson disease, essential tremor, and tremulous cervical dystonia.Proc Natl Acad Sci U S A. 2015 May 5;112(18):E2268. doi: 10.1073/pnas.1503105112. Epub 2015 Mar 30.

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  1. Lilleeng B, Gjerstad M, Baardsen R, Dalen I, Larsen JP. The long-term development of non-motor problems after STN-DBS. Acta Neurol Scand. 2015 Oct;132(4):251-8. doi: 10.1111/ane.12391. Epub 2015 Mar 6.

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  1. Forsaa EB, Larsen JP, Wentzel-Larsen T, Alves G. A 12-year population-based study of freezing of gait in Parkinson's disease. Parkinsonism Relat Disord 2015;21:254-8.
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  2. Lilleeng B, Gjerstad M, Baardsen R, Dalen I, Larsen JP. Motor symptoms after deep brain stimulation of the subthalamic nucleus. Acta Neurol Scand. 2015 May;131(5):298-304. doi: 10.1111/ane.12342. Epub 2014 Oct 23.

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  1. Abdullah R, Basak I, Patil KS, Alves G, Larsen JP, Møller SG. Parkinson's disease and age: The obvious but largely unexplored link. Exp Gerontol 2015;68:33-8.
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  2. Jami MS, Pal R, Hoedt E, Neubert TA, Larsen JP, Møller SG. Proteome analysis reveals roles of L-DOPA in response to oxidative stress in neurons. BMC Neurosci. 2014 Jul 31;15:93. doi: 10.1186/1471-2202-15-93.

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  1. Hiorth YH, Larsen JP, Lode K, Pedersen KF. Natural history of falls in a population-based cohort of patients with Parkinson's disease: an 8-year prospective study. Parkinsonism Relat Disord. 2014 Oct;20(10):1059-64. doi: 10.1016/j.parkreldis.2014.06.023. Epub 2014 Jul 9.

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  1. Björkblom B, Maple-Grødem J, Puno MR, Odell M, Larsen JP, Møller SG. Reactive oxygen species-mediated DJ-1 monomerization modulates intracellular trafficking involving karyopherin β2. Mol Cell Biol. 2014 Aug;34(16):3024-40. doi: 10.1128/MCB.00286-14. Epub 2014 Jun 9.

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  1. Patil KS, Basak I, Lee S, Abdullah R, Larsen JP, Møller SG. PARK13 regulates PINK1 and subcellular relocation patterns under oxidative stress in neurons. J Neurosci Res. 2014 Sep;92(9):1167-77. doi: 10.1002/jnr.23396. Epub 2014 May 2.

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  1. Pereira JB, Svenningsson P, Weintraub D, Brønnick K, Lebedev A, Westman E, Aarsland D. Initial cognitive decline is associated with cortical thinning in early Parkinson disease. Neurology. 2014 Jun 3;82(22):2017-25. doi: 10.1212/WNL.0000000000000483. Epub 2014 May 7.

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  1. Nagarajan A, Ning Y, Reisner K, Buraei Z, Larsen JP, Hobert O, Doitsidou M. Progressive degeneration of dopaminergic neurons through TRP channel-induced cell death. J Neurosci. 2014 Apr 23;34(17):5738-46. doi: 10.1523/JNEUROSCI.4540-13.2014.

PMID: 24760834

  1. Alves G, Lange J, Blennow K, Zetterberg H, Andreasson U, Førland MG, Tysnes OB, Larsen JP, Pedersen KF. CSF Aβ42 predicts early-onset dementia in Parkinson disease. Neurology 2014;82:1784-90.
    PMID: 24748671
  2. Basak I, Pal R, Patil KS, Dunne A, Ho HP, Lee S, Peiris D, Maple-Grødem J, Odell M, Chang EJ, Larsen JP, Møller SG. Arabidopsis AtPARK13, which confers thermotolerance, targets misfolded proteins. J Biol Chem. 2014 May 23;289(21):14458-69. doi: 10.1074/jbc.M114.548156. Epub 2014 Apr 9.

PMID: 24719325

  1. Brakedal B, Tysnes OB, Skeie GO, Larsen JP, Müller B. The factor structure of the UPDRS motor scores changes during early Parkinson's disease. Parkinsonism Relat Disord. 2014 Jun;20(6):617-21. doi: 10.1016/j.parkreldis.2014.03.008. Epub 2014 Mar 19.

PMID: 24685659

  1. Jacobsen C, Hagemeier J, Myhr KM, Nyland H, Lode K, Bergsland N, Ramasamy DP, Dalaker TO, Larsen JP, Farbu E, Zivadinov R. Brain atrophy and disability progression in multiple sclerosis patients: a 10-year follow-up study. J Neurol Neurosurg Psychiatry. 2014 Oct;85(10):1109-15. doi: 10.1136/jnnp-2013-306906. Epub 2014 Feb 19.

PMID: 24554101

  1. Lilleeng B, Brønnick K, Toft M, Dietrichs E, Larsen JP. Progression and survival in Parkinson's disease with subthalamic nucleus stimulation. Acta Neurol Scand. 2014 Nov;130(5):292-8. doi: 10.1111/ane.12224. Epub 2014 Feb 4.

PMID: 24495107

  1. Saleh S, Larsen JP, Bergsåker-Aspøy J, Grundt H. Re-admissions to hospital and patient satisfaction among patients with chronic obstructive pulmonary disease after telemedicine video consultation - a retrospective pilot study. Multidiscip Respir Med. 2014 Jan 30;9(1):6. doi: 10.1186/2049-6958-9-6.

PMID: 24475774

  1. Pal R, Alves G, Larsen JP, Møller SG. New insight into neurodegeneration: the role of proteomics. Mol Neurobiol 2014;49:1181-99.
    PMID: 24323427
  2. Hwang KS, Beyer MK, Green AE, Chung C, Thompson PM, Janvin C, Larsen JP, Aarsland D, Apostolova LG. Mapping cortical atrophy in Parkinson's disease patients with dementia. J Parkinsons Dis. 2013;3(1):69-76. doi: 10.3233/JPD-120151.

PMID: 23938313

  1. Müller B, Assmus J, Herlofson K, Larsen JP, Tysnes OB. Importance of motor vs. non-motor symptoms for health-related quality of life in early Parkinson's disease. Parkinsonism Relat Disord. 2013 Nov;19(11):1027-32. doi: 10.1016/j.parkreldis.2013.07.010. Epub 2013 Aug 2.

PMID: 23916654

  1. Björkblom B, Adilbayeva A, Maple-Grødem J, Piston D, Ökvist M, Xu XM, Brede C, Larsen JP, Møller SG. Parkinson disease protein DJ-1 binds metals and protects against metal-induced cytotoxicity. J Biol Chem. 2013 Aug 2;288(31):22809-20. doi: 10.1074/jbc.M113.482091. Epub 2013 Jun 21.

PMID: 23792957

  1. Klevan G, Jacobsen CO, Aarseth JH, Myhr KM, Nyland H, Glad S, Lode K, Figved N, Larsen JP, Farbu E. Health related quality of life in patients recently diagnosed with multiple sclerosis. Acta Neurol Scand. 2014 Jan;129(1):21-6. doi: 10.1111/ane.12142. Epub 2013 Jun 15.

PMID: 23772958

  1. Fjetland L, Roy S, Kurz KD, Solbakken T, Larsen JP, Kurz MW. Neurointerventional treatment in acute stroke. Whom to treat? (Endovascular treatment for acute stroke: utility of THRIVE score and HIAT score for patient selection). Cardiovasc Intervent Radiol. 2013 Oct;36(5):1241-6. doi: 10.1007/s00270-013-0636-9. Epub 2013 May 11.

PMID: 23665859

  1. Pedersen KF, Larsen JP, Tysnes OB, Alves G. Prognosis of Mild Cognitive Impairment in Early Parkinson Disease: The Norwegian ParkWest Study. JAMA Neurol 2013;70:580-6.
    PMID: 23529397
  2. Wörlund SM, Kurz MW, Hegland O, Brønnick K, Munk PS, Larsen JP. Treatment with statins improves long-term survival in individuals with carotid artery stenosis. Int J Cardiol. 2013 Sep 20;168(1):624-6. doi: 10.1016/j.ijcard.2013.01.198. Epub 2013 Feb 27.

PMID: 23452892

  1. Beyer MK, Alves G, Hwang KS, Babakchanian S, Bronnick KS, Chou YY, Dalaker TO, Kurz MW, Larsen JP, Somme JH, Thompson PM, Tysnes OB, Apostolova LG. Cerebrospinal fluid Aβ levels correlate with structural brain changes in Parkinson's disease. Mov Disord 2013;28:302-10.
    PMID: 23408705
  2. Tveiten OV, Skeie GO, Haugarvoll K, Müller B, Larsen JP, Tysnes OB. Treatment in early Parkinson's disease: the Norwegian ParkWest study. Acta Neurol Scand. 2013 Aug;128(2):107-13. doi: 10.1111/ane.12055. Epub 2012 Nov 29.

PMID: 23190324

  1. Alvseike H, Brønnick K. Feasibility of the iPad as a hub for smart house technology in the elderly; effects of cognition, self-efficacy, and technology experience. J Multidiscip Healthc. 2012;5:299-306. doi: 10.2147/JMDH.S35344. Epub 2012 Nov 28.

PMID: 23226024

  1. Beyer MK, Bronnick KS, Hwang KS, Bergsland N, Tysnes OB, Larsen JP, Thompson PM, Somme JH, Apostolova LG. Verbal memory is associated with structural hippocampal changes in newly diagnosed Parkinson's disease. J Neurol Neurosurg Psychiatry. 2013 Jan;84(1):23-8. doi: 10.1136/jnnp-2012-303054. Epub 2012 Nov 15.

PMID: 23154124

  1. Pihlstrøm L, Axelsson G, Bjørnarå KA, Dizdar N, Fardell C, Forsgren L, Holmberg B, Larsen JP, Linder J, Nissbrandt H, Tysnes OB, Ohman E, Dietrichs E, Toft M. Supportive evidence for 11 loci from genome-wide association studies in Parkinson's disease. Neurobiol Aging. 2013 Jun;34(6):1708.e7-13. doi: 10.1016/j.neurobiolaging.2012.10.019. Epub 2012 Nov 13.

PMID: 23153929

  1. Alves G, Pedersen KF, Bloem BR, Blennow K, Zetterberg H, Borm GF, Dalaker TO, Beyer MK, Aarsland D, Andreasson U, Lange J, Tysnes OB, Zivadinov R, Larsen JP. Cerebrospinal fluid amyloid-β and phenotypic heterogeneity in de novo Parkinson's disease. J Neurol Neurosurg Psychiatry 2013;84:537-45.
    PMID: 23117496
  2. Müller B, Assmus J, Larsen JP, Haugarvoll K, Skeie GO, Tysnes OB; ParkWest study group. Autonomic symptoms and dopaminergic treatment in de novo Parkinson's disease. Acta Neurol Scand. 2013 Apr;127(4):290-4. doi: 10.1111/ane.12010. Epub 2012 Sep 23.

PMID: 22998158

  1. Balafkan N, Tzoulis C, Müller B, Haugarvoll K, Tysnes OB, Larsen JP, Bindoff LA. Number of CAG repeats in POLG1 and its association with Parkinson disease in the Norwegian population. Mitochondrion. 2012 Nov;12(6):640-3. doi: 10.1016/j.mito.2012.08.004. Epub 2012 Aug 29.

PMID: 22963882

  1. Skeie GO, Muller B, Haugarvoll K, Larsen JP, Tysnes OB.Parkinson disease: associated disorders in the Norwegian population based incident ParkWest study. Parkinsonism Relat Disord. 2013 Jan;19(1):53-5. doi: 10.1016/j.parkreldis.2012.07.003. Epub 2012 Jul 26.

PMID: 22841686

  1. Hiorth YH, Lode K, Larsen JP. Frequencies of falls and associated features at different stages of Parkinson's disease.

Eur J Neurol. 2013 Jan;20(1):160-6. doi: 10.1111/j.1468-1331.2012.03821.x. Epub 2012 Jul 21.

PMID: 22816560

  1. Fjetland L, Roy S, Kurz KD, Larsen JP, Kurz MW. Endovascular acute stroke treatment performed by vascular interventional radiologists: is it safe and efficacious? Cardiovasc Intervent Radiol. 2012 Oct;35(5):1029-35. doi: 10.1007/s00270-012-0438-5. Epub 2012 Jun 30.

PMID: 22752101

  1. Stefansdottir S, Gjerstad MD, Tysnes OB, Larsen JP. Subjective sleep problems in patients with early Parkinson's disease. Eur J Neurol. 2012 Dec;19(12):1575-81. doi: 10.1111/j.1468-1331.2012.03791.x. Epub 2012 Jun 30.

PMID: 22747791

  1. Aurlien D, Larsen JP, Gjerstad L, Taubøll E. Comorbid and underlying diseases--major determinants of excess mortality in epilepsy. Seizure. 2012 Oct;21(8):573-7. doi: 10.1016/j.seizure.2012.05.015. Epub 2012 Jun 26.

PMID: 22743101

  1. Malmqvist S, Kjaermann I, Andersen K, Økland I, Brønnick K, Larsen JP. Prevalence of low back and pelvic pain during pregnancy in a Norwegian population. J Manipulative Physiol Ther. 2012 May;35(4):272-8. doi: 10.1016/j.jmpt.2012.04.004.

PMID: 22632586

  1. Munk PS, Isaksen K, Brønnick K, Kurz MW, Butt N, Larsen AI. Symptoms of anxiety and depression after percutaneous coronary intervention are associated with decreased heart rate variability, impaired endothelial function and increased inflammation. Int J Cardiol. 2012 Jun 28;158(1):173-6. doi: 10.1016/j.ijcard.2012.04.085. Epub 2012 May 8.

PMID: 22575625

  1. Herlofson K, Ongre SO, Enger LK, Tysnes OB, Larsen JP. Fatigue in early Parkinson's disease. Minor inconvenience or major distress? Eur J Neurol. 2012 Jul;19(7):963-8. doi: 10.1111/j.1468-1331.2012.03663.x. Epub 2012 Feb 16.

PMID: 22340430

  1. Aurlien D, Larsen JP, Gjerstad L, Taubøll E. Increased risk of sudden unexpected death in epilepsy in females using lamotrigine: a nested, case-control study. Epilepsia. 2012 Feb;53(2):258-66. doi: 10.1111/j.1528-1167.2011.03334.x. Epub 2011 Nov 29.

PMID: 22126371

  1. Gjerstad MD, Tysnes OB, Larsen JP. Increased risk of leg motor restlessness but not RLS in early Parkinson disease.

Neurology. 2011 Nov 29;77(22):1941-6. doi: 10.1212/WNL.0b013e31823a0cc8. Epub 2011 Nov 9.

PMID: 22076542

  1. Pedersen KF, Alves G, Larsen JP, Tysnes OB, Møller SG, Brønnick K. Psychometric properties of the Starkstein Apathy Scale in patients with early untreated Parkinson disease. Am J Geriatr Psychiatry. 2012 Feb;20(2):142-8. doi: 10.1097/JGP.0b013e31823038f2.

PMID: 22064613

  1. Vaccarino AL, Sills T, Anderson KE, Bachoud-Lévi AC, Borowsky B, Craufurd D, Duff K, Giuliano J, Groves M, Guttman M, Kupchak P, Ho AK, Paulsen JS, Pedersen KF, van Duijn E, van Kammen DP, Evans K. Assessment of depression, anxiety and apathy in prodromal and early huntington disease. PLoS Curr. 2011 Jun 17;3:RRN1242. doi: 10.1371/currents.RRN1242.

PMID: 21731882

  1. Vossius C, Larsen JP, Janvin C, Aarsland D. The economic impact of cognitive impairment in Parkinson's disease.

Mov Disord. 2011 Jul;26(8):1541-4. doi: 10.1002/mds.23661. Epub 2011 Apr 29.

PMID: 21538519

  1. Aarsland D, Brønnick K, Fladby T. Mild cognitive impairment in Parkinson's disease. Curr Neurol Neurosci Rep. 2011 Aug;11(4):371-8. doi: 10.1007/s11910-011-0203-1.

PMID: 21487730

  1. Bronnick K, Emre M, Tekin S, Haugen SB, Aarsland D. Cognitive correlates of visual hallucinations in dementia associated with Parkinson's disease. Mov Disord. 2011 Apr;26(5):824-9. doi: 10.1002/mds.23525. Epub 2011 Mar 21.

PMID: 21437985

  1. Aarstad AK, Lode K, Larsen JP, Bru E, Aarstad HJ. Choice of psychological coping in laryngectomized, head and neck squamous cell carcinoma patients versus multiple sclerosis patients. Eur Arch Otorhinolaryngol. 2011 Jun;268(6):907-15. doi: 10.1007/s00405-010-1417-6. Epub 2010 Nov 18.

PMID: 21085978

  1. Bronnick K, Alves G, Aarsland D, Tysnes OB, Larsen JP. Verbal memory in drug-naive, newly diagnosed Parkinson's disease. The retrieval deficit hypothesis revisited. Neuropsychology 2011;25:114-124.
    PMID: 220954781
  2. Apostolova L, Alves G, Hwang KS, Babakchanian S, Bronnick KS, Larsen JP, Thompson PM, Chou YY, Tysnes OB, Vefring HK, Beyer MK. Hippocampal and ventricular changes in Parkinson's disease mild cognitive impairment. Neurobiol Aging 2012;33:2113-24.
    PMID: 21813212
  3. Dalaker TO, Zivadinov R, Ramasamy DP, Beyer MK, Alves G, Bronnick KS, Tysnes OB, Aarsland D, Larsen JP. Ventricular enlargement and mild cognitive impairment in early Parkinson's disease. Mov Disord 2011;26:297-301.
    PMID: 21412836
  4. Mulugeta E, Londos E, Ballard C, Alves G, Zetterberg H, Blennow K, Skogseth R, Minthon L, Aarsland D. CSF amyloid β38 as a novel diagnostic marker for dementia with Lewy bodies. J Neurol Neurosurg Psychiatry 2011;82:160-4.
    PMID: 21047883
  5. Müller B, Larsen JP, Wentzel-Larsen T, Skeie GO, Tysnes OB; Parkwest Study Group. Autonomic and sensory symptoms and signs in incident, untreated Parkinson's disease: frequent but mild. Mov Disord. 2011 Jan;26(1):65-72. doi: 10.1002/mds.23387. Epub 2010 Oct 5.

PMID: 20925070

  1. Forsaa EB, Larsen JP, Wentzel-Larsen T, Alves G. What predicts mortality in Parkinson disease?: a prospective population-based long-term study. Neurology 2010;75:1270-6.
    PMID: 20697051
  2. Forsaa EB, Larsen JP, Wentzel-Larsen T, Goetz CG, Stebbins GT, Aarsland D, Alves G. A 12-year population-based study of psychosis in Parkinson disease. Arch Neurol 2010;67:996-1001.
    PMID: 20697051
  3. Skeie GO, Muller B, Haugarvoll K, Larsen JP, Tysnes OB. Differential effect of environmental risk factors on postural instability gait difficulties and tremor dominant Parkinson's disease. Mov Disord. 2010 Sep 15;25(12):1847-52. doi: 10.1002/mds.23178.

PMID: 20669310

  1. Tysnes OB, Müller B, Larsen JP. Are dysautonomic and sensory symptoms present in early Parkinson's disease?

Acta Neurol Scand Suppl. 2010;(190):72-7. doi: 10.1111/j.1600-0404.2010.01380.x.

PMID: 20586740

  1. Alves G, Bronnick K, Aarsland D, Blennow K, Zetterberg H, Ballard C, Kurz MW, Andreasson U, Tysnes OB, Larsen JP, Mulugeta E. CSF amyloid-beta and tau proteins, and cognitive performance, in early and untreated Parkinson’s disease: the Norwegian ParkWest study. J Neurol Neurosurg Psychiatry 2010;81:1080-6.
    PMID: 20547614
  2. Aarsland D, Kurz MW. The epidemiology of dementia associated with Parkinson's disease. Brain Pathol. 2010 May;20(3):633-9. doi: 10.1111/j.1750-3639.2009.00369.x.

PMID: 20522088

  1. Vefring H, Haugarvoll K, Tysnes OB, Larsen JP, Kurz MW; Norwegian ParkWest Study group. The role of APOE alleles in incident Parkinson's disease. The Norwegian ParkWest Study. Acta Neurol Scand. 2010 Dec;122(6):438-41. doi: 10.1111/j.1600-0404.2010.01362.x.

PMID: 20456244

  1. Apostolova LG, Beyer M, Green AE, Hwang KS, Morra JH, Chou YY, Avedissian C, Aarsland D, Janvin CC, Larsen JP, Cummings JL, Thompson PM. Hippocampal, caudate, and ventricular changes in Parkinson's disease with and without dementia. Mov Disord. 2010 Apr 30;25(6):687-95. doi: 10.1002/mds.22799.

PMID: 20437538

  1. Xu XM, Lin H, Maple J, Björkblom B, Alves G, Larsen JP, Møller SG. The Arabidopsis DJ-1a protein confers stress protection through cytosolic SOD activation. J Cell Sci. 2010 May 15;123(Pt 10):1644-51. doi: 10.1242/jcs.063222. Epub 2010 Apr 20.

PMID: 20406884

  1. Schmitt FA, Aarsland D, Brønnick KS, Meng X, Tekin S, Olin JT. Evaluating rivastigmine in mild-to-moderate Parkinson's disease dementia using ADAS-cog items. Am J Alzheimers Dis Other Demen. 2010 Aug;25(5):407-13. doi: 10.1177/1533317510367486. Epub 2010 Apr 14.

PMID: 20392860

  1. Dalaker TO, Zivadinov R, Larsen JP, Beyer MK, Cox JL, Alves G, Bronnick K, Tysnes OB, Antulov R, Dwyer MG, Aarsland D. Gray matter correlations of cognition in incident Parkinson's disease. Mov Disord 2010;25:629-33.
    PMID: 20213820
  2. Leiknes I, Tysnes OB, Aarsland D, Larsen JP. Caregiver distress associated with neuropsychiatric problems in patients with early Parkinson's disease: the Norwegian ParkWest study. Acta Neurol Scand. 2010 Dec;122(6):418-24. doi: 10.1111/j.1600-0404.2010.01332.x.

PMID: 20175757

  1. Testad I, Ballard C, Brønnick K, Aarsland D. The effect of staff training on agitation and use of restraint in nursing home residents with dementia: a single-blind, randomized controlled trial. J Clin Psychiatry. 2010 Jan;71(1):80-6. doi: 10.4088/JCP.09m05486oli.

PMID: 20129008

  1. Lode K, Bru E, Klevan G, Myhr KM, Nyland H, Larsen JP. Coping with multiple sclerosis: a 5-year follow-up study. Acta Neurol Scand. 2010 Nov;122(5):336-42. doi: 10.1111/j.1600-0404.2009.01313.x.

PMID: 20047563

  1. Xu XM, Lin H, Maple J, Björkblom B, Alves G, Larsen JP, Møller SG. The Arabidopsis DJ-1a protein confers stress protection through cytosolic SOD activation. J Cell Sci 2010; 123:1644-51.
    PMID: 20406884
  2. Friedman JH, Alves G, Hagell P, Marinus J, Marsh L, Martinez-Martin P, Goetz CG, Poewe W, Rascol O, Sampaio C, Stebbins G, Schrag A. Fatigue rating scales critique and recommendations by the Movement Disorders Society task force on rating scales for Parkinson's disease. Mov Disord 2010;25:805-22.
    PMID: 20461797
  3. Hegland O, Kurz MW, Munk PS, Larsen JP. The effect of statin therapy on the progression of carotid artery stenosis in relation to stenosis severity. Acta Neurol Scand. 2010 Jan;121(1):11-5. doi: 10.1111/j.1600-0404.2009.01280.x.

PMID: 19919642

  1. Fenelon G, Alves G. Epidemiology of psychosis in Parkinson’s disease. J Neurol Sci 2010;15:289:12-7.
    PMID: 19740486
  2. Ehrt U, Broich K, Larsen JP, Ballard C, Aarsland D. Use of drugs with anticholinergic effect and impact on cognition in Parkinson's disease: a cohort study. J Neurol Neurosurg Psychiatry. 2010 Feb;81(2):160-5. doi: 10.1136/jnnp.2009.186239. Epub 2009 Sep 21.

PMID: 19770163

  1. Vossius C, Nilsen OB, Larsen JP. Parkinson's disease and hospital admissions: frequencies, diagnoses and costs.

Acta Neurol Scand. 2010 Jan;121(1):38-43. doi: 10.1111/j.1600-0404.2009.01239.x.

PMID: 19744137

  1. Aarsland D, Kurz MW. The epidemiology of dementia associated with Parkinson disease. J Neurol Sci. 2010 Feb 15;289(1-2):18-22. doi: 10.1016/j.jns.2009.08.034.

PMID: 19733364

  1. Pedersen KF, Alves G, Brønnick K, Aarsland D, Tysnes OB, Larsen JP. Apathy in drug-naïve patients with incident Parkinson's disease: the Norwegian ParkWest study. J Neurol 2010;257:217-23.
    PMID: 19705051

 

Selected publications before 2010:

 

  1. Alves G, Müller B, Herlofson K, HogenEsch I, Telstad W, Aarsland D, Tysnes OB, Larsen JP. Incidence of Parkinson’s disease in Norway. The Norwegian ParkWest study. J Neurol Neurosurgery Psychiatry 2009;80:851-7.
    PMID: 19246476
  2. Aarsland D, Ballard C, Walker Z, Bostrom F, Alves G, Kossakowski K, Leroi I, Pozo-Rodriguez F, Minthon L, Londos E. Memantine in patients with Parkinson's disease dementia or dementia with Lewy bodies: a double-blind, placebo-controlled, multicentre trial. Lancet Neurol 2009;8:613-8.
    PMID: 19520613
  3. Aarsland D, Bronnick K, Larsen JP, Tysnes OB, Alves G. Cognitive impairment in incident, untreated Parkinson disease: The Norwegian ParkWest study. Neurology 2009,72:1121-6.
    PMID: 19020293
  4. Buter TC, van den Hout A, Matthews FE, Larsen JP, Brayne C, Aarsland D. Dementia and survival in Parkinson disease: a 12-year population study. Neurology. 2008 Mar 25;70(13):1017-22. doi: 10.1212/01.wnl.0000306632.43729.24.

PMID: 18362281

  1. Aarsland D, Kvaløy JT, Andersen K, Larsen JP, Tang MX, Lolk A, Kragh-Sørensen P, Marder K. The effect of age of onset of PD on risk of dementia. J Neurol. 2007 Jan;254(1):38-45. doi: 10.1007/s00415-006-0234-8. Epub 2007 Feb 14.

PMID: 17508138

  1. Ballard C, Ziabreva I, Perry R, Larsen JP, O'Brien J, McKeith I, Perry E, Aarsland D. Differences in neuropathologic characteristics across the Lewy body dementia spectrum. Neurology. 2006 Dec 12;67(11):1931-4. doi: 10.1212/01.wnl.0000249130.63615.cc.

PMID: 17159096

  1. Gjerstad MD, Alves G, Wentzel-Larsen T, Aarsland D, Larsen JP. Excessive daytime sleepiness in Parkinson disease: is it the drugs or the disease? Neurology 2006;67:853-858.
    PMID: 16966550
  2. Alves G, Aarsland D, Wentzel-Larsen T, Larsen JP. The progression of motor symptoms and disability in Parkinson disease: a population-based study. Neurology 2005,65:1436-1441.
    PMID: 16275832
  3. Aarsland D, Perry R, Brown A, Larsen JP, Ballard C. Neuropathology of dementia in Parkinson's disease: a prospective, community-based study. Ann Neurol. 2005 Nov;58(5):773-6. doi: 10.1002/ana.20635.

PMID: 16240351

  1. Aarsland D, Andersen K, Larsen JP, Perry R, Wentzel-Larsen T, Lolk A, Kragh-Sørensen P. The rate of cognitive decline in Parkinson disease. Arch Neurol. 2004 Dec;61(12):1906-11. doi: 10.1001/archneur.61.12.1906.

PMID: 15596611

  1. Herlofson K, Lie SA, Arsland D, Larsen JP. Mortality and Parkinson disease: A community based study.

Neurology. 2004 Mar 23;62(6):937-42. doi: 10.1212/01.wnl.0000115116.56955.50.

PMID: 15037696

  1. Aarsland D, Andersen K, Larsen JP, Lolk A, Kragh-Sørensen P. Prevalence and characteristics of dementia in Parkinson disease: an 8-year prospective study. Arch Neurol. 2003 Mar;60(3):387-92. doi: 10.1001/archneur.60.3.387.

PMID: 12633150

  1. Gjerstad MD, Aarsland D, Larsen JP. Development of daytime somnolence over time in Parkinson's disease. Neurology. 2002 May 28;58(10):1544-6. doi: 10.1212/wnl.58.10.1544.

PMID: 12034797

  1. Aarsland D, Laake K, Larsen JP, Janvin C. Donepezil for cognitive impairment in Parkinson's disease: a randomised controlled study. J Neurol Neurosurg Psychiatry. 2002 Jun;72(6):708-12. doi: 10.1136/jnnp.72.6.708.

PMID: 12023410

  1. Larsen JP, Boas J, Erdal JE. Does selegiline modify the progression of early Parkinson's disease? Results from a five-year study. The Norwegian-Danish Study Group. Eur J Neurol. 1999 Sep;6(5):539-47. doi: 10.1046/j.1468-1331.1999.650539.x.

PMID: 10457386

  1. Aarsland D, Tandberg E, Larsen JP, Cummings JL. Frequency of dementia in Parkinson disease. Arch Neurol. 1996 Jun;53(6):538-42. doi: 10.1001/archneur.1996.00550060082020.

PMID: 8660156

  1. Tandberg E, Larsen JP, Nessler EG, Riise T, Aarli JA. The epidemiology of Parkinson's disease in the county of Rogaland, Norway. Mov Disord. 1995 Sep;10(5):541-9. doi: 10.1002/mds.870100503.

PMID: 8552103

  1. Larsen JP. Parkinson's disease as community health problem: study in Norwegian nursing homes. The Norwegian Study Group of Parkinson's Disease in the Elderly. BMJ. 1991 Sep 28;303(6805):741-3. doi: 10.1136/bmj.303.6805.741.

PMID: 1932932

 

 

 

Last updated 3/6/2024